There is an old line about someone seeing a pro baseball player and saying, "That guy is wealthy." His father or someone saying, "No, he is rich. The guy paying his salary is wealthy."
A-List actors are rich. Like pro athletes, they know their careers can be ended in a moment by the wealthy people who pay their salaries.
The Clooney's have enough wealth and power to make this step. 99% of other actors, including a large percentage of A-listers, do not.
Anyone who stays long in that industry, especially in front of the camera, knows how the system works.
Those who risk their careers like Amal Clooney are truly heroes.